COMPANY

Regenexx

Keywords: musculoskeletal Knee Osteoarthritis Craniocervical Injuries Lumbosacral Radiculopathy Lumbar Radiculopathy Orthopedic Disorder Degenerative Disc Disease Rotator Cuff Tear Anterior Cruciate Ligament Tear Low Back Pain Covid19 Radiculopathy Herniated Disc Disc Degeneration Bone Marrow Concentrate treatment

Profile checked Oct 10, 2026

16Trials (company is sponsor)

Timeline

Jul 1, 2025 Trial start Not phased (device or behavioral study): Platelet Lysate vs Saline for Lumbosacral Radiculopathy source ↗
May 6, 2022 Trial start Not phased (device or behavioral study): Trial for Treating Painful Degenerative Disc Disease source ↗
Feb 3, 2021 Trial start Not phased (device or behavioral study): Randomized Trial of Regenexx Stem Cell Support Formula source ↗
Dec 8, 2020 Trial start Not phased (device or behavioral study): Nebulized PL for Post-COVID-19 Syndrome source ↗
May 2, 2019 Trial start Not phased (device or behavioral study): A Trial Comparing Three Orthobiologic Therapies on Atrophied Multifidus Muscles in Patients With Low Back Pain source ↗
Mar 21, 2019 Trial start Not phased (device or behavioral study): Correlating the OA Knee Microenvironment to Outcomes After Regenexx-SD Treatment: A Multi-Site Study source ↗
Aug 20, 2018 Trial start —: Case Series on Using Bone Marrow Concentrate for Alar Ligament Injuries source ↗
Mar 23, 2018 Trial start Not phased (device or behavioral study): Use of Bone Marrow Concentrate for Treatment of Alar, Accessory, and Transverse Ligament Injuries source ↗
2016-07 Trial start Phase 1: Catabolic Marker Levels After Platelet Poor Plasma (PPP) Lavage source ↗
2016-02 Trial start —: A Clinical Registry of Orthobiologics Procedures source ↗
Sep 8, 2015 Trial start Phase 3: Correlating the Osteoarthritic Knee Microenvironment to Clinical Outcome After Treatment With Regenexx®SD Treatment source ↗
2015-02 Trial start —: A Controlled Surveillance of the Osteoarthritic Knee Microenvironment With Regenexx® SD Treatment source ↗
2014-01 Trial start Not phased (device or behavioral study): Regenexx™ SD Versus Exercise Therapy for Treatment of Knee Osteoarthritis With Historical Comparison to TKA source ↗
2013-05 Trial start Not phased (device or behavioral study): Regenexx™ SD Versus Exercise Therapy for ACL Tears source ↗
2013-05 Trial start Not phased (device or behavioral study): Regenexx™ PL-Disc Versus Steroid Epidurals for Lumbar Radiculopathy source ↗
2013-02 Trial start Not phased (device or behavioral study): Regenexx™ SD Versus Exercise Therapy for Rotator Cuff Tears source ↗

Upcoming milestones

Dec 31, 2026 (ESTIMATED) · Not phased · Trial for Treating Painful Degenerative Disc Disease · NCT05287867
2030-12 (ESTIMATED) · Not phased · Use of Bone Marrow Concentrate for Treatment of Alar, Accessory, and Transverse Ligament Injuries · NCT03517761
2036-02 (ESTIMATED) · · A Clinical Registry of Orthobiologics Procedures · NCT03011398

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 16

Record	Title	Phase	Status	Start	Primary completion
NCT06924853	Platelet Lysate vs Saline for Lumbosacral Radiculopathy	Not phased (device or behavioral study)	Terminated	Jul 1, 2025	Nov 5, 2025 (actual)
NCT03011398	A Clinical Registry of Orthobiologics Procedures	Not listed	Enrolling by invitation	2016-02	2036-02 (estimated)
NCT05287867	Trial for Treating Painful Degenerative Disc Disease	Not phased (device or behavioral study)	Recruiting	May 6, 2022	Dec 31, 2026 (estimated)
NCT03517761	Use of Bone Marrow Concentrate for Treatment of Alar, Accessory, and Transverse Ligament Injuries	Not phased (device or behavioral study)	Recruiting	Mar 23, 2018	2030-12 (estimated)
NCT03898388	Correlating the OA Knee Microenvironment to Outcomes After Regenexx-SD Treatment: A Multi-Site Study	Not phased (device or behavioral study)	Terminated	Mar 21, 2019	Oct 30, 2020 (actual)
NCT04661267	Randomized Trial of Regenexx Stem Cell Support Formula	Not phased (device or behavioral study)	Completed	Feb 3, 2021	Oct 31, 2022 (actual)
NCT01788683	Regenexx™ SD Versus Exercise Therapy for Rotator Cuff Tears	Not phased (device or behavioral study)	Completed	2013-02	Aug 28, 2020 (actual)
NCT01850758	Regenexx™ SD Versus Exercise Therapy for ACL Tears	Not phased (device or behavioral study)	Completed	2013-05	May 22, 2020 (actual)
NCT02848027	Correlating the Osteoarthritic Knee Microenvironment to Clinical Outcome After Treatment With Regenexx®SD Treatment	Phase 3	Completed	Sep 8, 2015	Jun 30, 2020 (actual)
NCT03618979	A Trial Comparing Three Orthobiologic Therapies on Atrophied Multifidus Muscles in Patients With Low Back Pain	Not phased (device or behavioral study)	Terminated	May 2, 2019	Jun 29, 2022 (actual)
NCT04487691	Nebulized PL for Post-COVID-19 Syndrome	Not phased (device or behavioral study)	Terminated	Dec 8, 2020	Jun 15, 2021 (actual)
NCT03120988	Catabolic Marker Levels After Platelet Poor Plasma (PPP) Lavage	Phase 1	Completed	2016-07	Jun 30, 2017 (actual)
NCT03557606	Case Series on Using Bone Marrow Concentrate for Alar Ligament Injuries	Not listed	Withdrawn	Aug 20, 2018	May 1, 2023 (estimated)
NCT02034032	Regenexx™ SD Versus Exercise Therapy for Treatment of Knee Osteoarthritis With Historical Comparison to TKA	Not phased (device or behavioral study)	Completed	2014-01	2018-06 (actual)
NCT02370823	A Controlled Surveillance of the Osteoarthritic Knee Microenvironment With Regenexx® SD Treatment	Not listed	Terminated	2015-02	2018-03 (actual)
NCT01850771	Regenexx™ PL-Disc Versus Steroid Epidurals for Lumbar Radiculopathy	Not phased (device or behavioral study)	Terminated	2013-05	2016-05 (actual)