COMPANY

NeuroSigma, Inc.

HQ: Los Angeles, CA source · neurosigma.com ↗ · West Coast

FDA-cleared device company

Also known as NeuroSigma · 13 sources

Keywords: neurology neuromodulation epilepsy Seizure Disorder External Trigeminal Nerve Stimulation

Location: Los Angeles, CA · source · Oct 14, 2026

Profile checked Oct 10, 2026

1Trials (company is sponsor)12NIH grants

Timeline

2012-06 Trial start Not phased (device or behavioral study): External Trigeminal Nerve Stimulation for Drug Resistent Epilepsy source ↗

Clinical trials (lead sponsor) 1

Record	Title	Phase	Status	Start	Primary completion
NCT01978470	External Trigeminal Nerve Stimulation for Drug Resistent Epilepsy	Not phased (device or behavioral study)	Unknown status (ClinicalTrials.gov)	2012-06	2016-06 (estimated)

NIH awards 12

Annual award amounts. Total $7.4M.

Mar 11, 2019 NIH award 5U44NS081840-04 FY2019: $925,538 awarded for that fiscal year; activity U44 (SBIR); PI COOK, IAN A; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Development of an Implantable Trigeminal Nerve St source ↗
Sep 19, 2018 NIH award 1R43HL140895-01 FY2018: $415,743 awarded for that fiscal year; activity R43 (SBIR); PI KEALEY, COLIN PATRICK; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Development of an Anti-Embolic Micromes source ↗
Feb 15, 2018 NIH award 5R42NS074576-05 FY2018: $976,739 awarded for that fiscal year; activity R42 (STTR); PI KEALEY, COLIN PATRICK; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Preclinical Testing of a Novel Flow Div source ↗
Mar 3, 2017 NIH award 5R42NS074576-04 FY2017: $899,775 awarded for that fiscal year; activity R42 (STTR); PI KEALEY, COLIN PATRICK; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Preclinical Testing of a Novel Flow Div source ↗
Feb 18, 2016 NIH award 2R42NS074576-03 FY2016: $1,072,694 awarded for that fiscal year; activity R42 (STTR); PI KEALEY, COLIN PATRICK; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Preclinical Testing of a Novel Flow D source ↗
Sep 19, 2015 NIH award 4U44NS081840-03 FY2015: $1,052,780 awarded for that fiscal year; activity U44 (SBIR); PI COOK, IAN A; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Development of an Implantable Trigeminal Nerve source ↗
Feb 14, 2014 NIH award 5U44NS081840-02 FY2014: $313,545 awarded for that fiscal year; activity U44 (SBIR); PI COOK, IAN A; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Development of an Implantable Trigeminal Nerve St source ↗
Aug 13, 2013 NIH award 5R41NS074576-02 FY2013: $339,690 awarded for that fiscal year; activity R41 (STTR); PI JOHNSON, ALFRED DAVID; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Preclinical Testing of a Novel Flow Div source ↗
Jan 30, 2013 NIH award 1U44NS081840-01 FY2013: $305,058 awarded for that fiscal year; activity U44 (SBIR); PI DEGIORGIO, CHRISTOPHER; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Development of an Implantable Trigemin source ↗
Jul 17, 2012 NIH award 5R41NS076014-02 FY2012: $328,608 awarded for that fiscal year; activity R41 (STTR); PI COOK, IAN A; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Trigeminal Nerve Stimulation for Epilepsy source ↗
Aug 16, 2011 NIH award 1R41NS076014-01 FY2011: $418,261 awarded for that fiscal year; activity R41 (STTR); PI DEGIORGIO, CHRISTOPHER; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Trigeminal Nerve Stimulation for Epile source ↗
Aug 15, 2011 NIH award 1R41NS074576-01 FY2011: $342,847 awarded for that fiscal year; activity R41 (STTR); PI JOHNSON, ALFRED DAVID; recipient as written: NEUROSIGMA, INC., LOS ANGELES, CA. Preclinical Testing of a Novel Flow Div source ↗