COMPANY

Medley Therapeutics

HQ: Laguna Hills, CA source · medleytx.com ↗

Location: Laguna Hills, CA · source · Oct 14, 2026

Profile checked Oct 10, 2026

Keywords: Heart Failure With Reduced Ejection Fraction YAP101 (AAV9-Sav-shRNA)

Timeline

Apr 23, 2025 Trial start Phase 1: Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure source ↗

2026-12 (ESTIMATED) · Phase 1 · Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure · NCT06831825

Estimated primary completion per ClinicalTrials.gov. Dates move.

Record	Title	Phase	Status	Start	Primary completion
NCT06831825	Study Assessing Left Ventricular Administration of a Genetic Medicine Directing Organ Regeneration in Heart Failure	Phase 1	Recruiting	Apr 23, 2025	2026-12 (estimated)