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COMPANY

Bexion Pharmaceuticals

HQ: Covington, KY source · bexionpharma.com ↗ · Southeast

Clinical Phase 2

Keywords: oncology cancer glioblastoma multiforme Metastatic Colorectal Carcinoma Neuropathy Chemotherapy-induced Peripheral Neuropathy Diffuse Intrinsic Pontine Glioma H3 K27M-Mutant Diffuse Midline Glioma pancreatic cancer prostate cancer BXQ-350

Location: Covington, KY · source · Oct 15, 2026

Profile checked Oct 10, 2026

6Trials (company is sponsor)8NIH grants

Timeline

  1. Trial start Phase 1/Phase 2: BXQ-350 in Newly Diagnosed Metastatic Colorectal Carcinoma source ↗
  2. Trial start Early phase 1: BXQ-350 Pharmacokinetic/Pharmacodynamic Study in Cancer Patients source ↗
  3. Trial start Phase 1: A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG) source ↗
  4. Trial start Phase 1: Continued Treatment for Participants Enrolled in Studies of BXQ-350 source ↗
  5. Trial start Phase 1: A Study of BXQ-350 in Children and Young Adults With Relapsed Solid Tumors source ↗
  6. Trial start 1: Phase 1 Study of BXQ-350 in Adult Patients With Advanced Solid Tumors source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 6

RecordTitlePhaseStatusStartPrimary completion
NCT05322590BXQ-350 in Newly Diagnosed Metastatic Colorectal CarcinomaPhase 1/Phase 2Active, not recruitingJan 9, 20232026-11 (estimated)
NCT05291286BXQ-350 Pharmacokinetic/Pharmacodynamic Study in Cancer PatientsEarly phase 1CompletedOct 17, 2022Dec 20, 2024 (actual)
NCT04404569Continued Treatment for Participants Enrolled in Studies of BXQ-350Phase 1TerminatedJun 8, 2020Sep 23, 2024 (actual)
NCT04771897A Study of BXQ-350 in Children With Newly Diagnosed Diffuse Intrinsic Pontine Glioma (DIPG) or Diffuse Midline Glioma (DMG)Phase 1TerminatedMay 24, 2021Oct 4, 2024 (actual)
NCT02859857Phase 1 Study of BXQ-350 in Adult Patients With Advanced Solid Tumors1CompletedSep 1, 2016Jun 17, 2019 (actual)
NCT03967093A Study of BXQ-350 in Children and Young Adults With Relapsed Solid TumorsPhase 1TerminatedApr 15, 2019Jan 3, 2020 (actual)

NIH awards 8

Annual award amounts. Total $4.9M.

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