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COMPANY

Aardvark Therapeutics

HQ: San Diego, CA source · aardvarktherapeutics.com ↗

Clinical Phase 3

Aardvark Therapeutics is a clinical-stage biopharmaceutical company developing, small-molecule therapies designed to inhibit hunger and treat metabolic diseases. Aardvark is developing compounds that target Bitter Taste Receptors (TAS2Rs) to address hunger-associated conditions. From company website Source · Oct 13, 2026

Keywords: clinical-stage Prader-Willi Syndrome Hyperphagia Obesity Hyperphagia in Prader-Willi Syndrome Autism Spectrum Disorder Bariatric Surgery Weight Gain ARD-101

Location: San Diego, CA · source · Oct 14, 2026

Profile checked Oct 10, 2026

$94.2MRaised (2 yrs)6Trials (company is sponsor)

Timeline

  1. Raise IPO: $94.2M (total, as published), announced Feb 13, 2025. Source: company release on GlobeNewswire. source ↗
  2. Trial start Phase 3: ARD-101 for Treatment of PWS: The Hunger Elimination or Reduction Objective Trial source ↗
  3. Trial start Phase 2: A Study to Evaluate ARD-501 in Patients With Autism Spectrum Disorder source ↗
  4. Trial start Phase 3: The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OLE) Trial source ↗
  5. Trial start Phase 2: A Study of Oral ARD-101 in Patients With Prader-Willi Syndrome source ↗
  6. Trial start Phase 2: Study to Evaluate ARD-101 in Adults Receiving Bariatric Surgery source ↗
  7. Trial start Phase 2: Study to Evaluate ARD-101 in Adults With Obesity source ↗

Funding

Raised: $94.2M. Last 2 years.

Clinical trials (lead sponsor) 6

RecordTitlePhaseStatusStartPrimary completion
NCT05153434A Study of Oral ARD-101 in Patients With Prader-Willi SyndromePhase 2CompletedMay 27, 2022Sep 24, 2024 (actual)
NCT06828861ARD-101 for Treatment of PWS: The Hunger Elimination or Reduction Objective TrialPhase 3TerminatedDec 20, 2024May 7, 2026 (actual)
NCT07197034The Hunger Elimination or Reduction Objective (HERO ) Open -Label Extension (OLE) TrialPhase 3TerminatedJul 23, 2024Apr 15, 2026 (actual)
NCT06126653A Study to Evaluate ARD-501 in Patients With Autism Spectrum DisorderPhase 2CompletedAug 1, 2024Jan 13, 2025 (actual)
NCT05215847Study to Evaluate ARD-101 in Adults Receiving Bariatric SurgeryPhase 2CompletedMar 1, 2022Feb 3, 2023 (actual)
NCT05121441Study to Evaluate ARD-101 in Adults With ObesityPhase 2CompletedNov 15, 2021Nov 9, 2022 (actual)

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