COMPANY

Mebias Discovery

HQ: New Haven, CT source · mebiasdiscovery.com ↗ · New England

Mebias Discovery's website says: "MEBIAS’ business model is comprised of advancing and partnering Mebias’ wholly owned molecules into early clinical development." From company website Source · Oct 13, 2026

Keywords: molecules opioid use disorder MEB-1170

Profile checked Oct 10, 2026

1Trials (company is sponsor)9NIH grants

Timeline

Nov 15, 2022 Trial start Phase 1: A Study to Assess the Safety of MEB-1170 in Healthy Subjects source ↗

Clinical trials (lead sponsor) 1

Record	Title	Phase	Status	Start	Primary completion
NCT05748119	A Study to Assess the Safety of MEB-1170 in Healthy Subjects	Phase 1	Unknown status (ClinicalTrials.gov)	Nov 15, 2022	Oct 1, 2023 (estimated)

NIH awards 9

Annual award amounts. Total $14.3M.

Jun 23, 2025 NIH award 1UG3DA063357-01 FY2025: $4,710,576 awarded for that fiscal year; activity UG3 (OTHER_NIH); PI KUO, LAWRENCE C; recipient as written: MEBIAS DISCOVERY, INC., NEW HAVEN, CT. MEB-1170: A New Chemical Entity fo source ↗
Jun 21, 2023 NIH award 3UH3DA047700-05S2 FY2023: $109,995 awarded for that fiscal year; activity UH3 (OTHER_NIH); PI KUO, LAWRENCE C; recipient as written: MEBIAS DISCOVERY, INC., NEW HAVEN, CT. Biased Mu-Opioid Receptor Analgesi source ↗
Sep 13, 2022 NIH award 3UH3DA047700-05S1 FY2022: $109,999 awarded for that fiscal year; activity UH3 (OTHER_NIH); PI KUO, LAWRENCE C; recipient as written: MEBIAS DISCOVERY, INC., NEW HAVEN, CT. Biased Mu-Opioid Receptor Analgesi source ↗
Aug 24, 2022 NIH award 5UH3DA047700-05 FY2022: $1,995,232 awarded for that fiscal year; activity UH3 (OTHER_NIH); PI KUO, LAWRENCE C; recipient as written: MEBIAS DISCOVERY, INC., NEW HAVEN, CT. Biased Mu-Opioid Receptor Analgesi source ↗
Mar 15, 2022 NIH award 3UH3DA047700-04S1 FY2022: $94,999 awarded for that fiscal year; activity UH3 (OTHER_NIH); PI KUO, LAWRENCE C; recipient as written: MEBIAS DISCOVERY, INC., NEW HAVEN, CT. Biased Mu-Opioid Receptor Analgesic source ↗
Aug 31, 2021 NIH award 5UH3DA047700-04 FY2021: $1,996,702 awarded for that fiscal year; activity UH3 (OTHER_NIH); PI KUO, LAWRENCE C; recipient as written: MEBIAS DISCOVERY, INC., NEW HAVEN, CT. Biased Mu-Opioid Receptor Analgesi source ↗
Sep 1, 2020 NIH award 4UH3DA047700-03 FY2020: $3,146,950 awarded for that fiscal year; activity UH3 (OTHER_NIH); PI KUO, LAWRENCE C; recipient as written: MEBIAS DISCOVERY, INC., NEW HAVEN, CT. Biased Mu-Opioid Receptor Analgesi source ↗
Aug 29, 2019 NIH award 6UG3DA047700-02 FY2019: $1,263,814 awarded for that fiscal year; activity UG3 (OTHER_NIH); PI KUO, LAWRENCE C; recipient as written: MEBIAS DISCOVERY, INC., NEW HAVEN, CT. Biased Mu-Opioid Receptor Analgesi source ↗
Sep 6, 2018 NIH award 1UG3DA047700-01 FY2018: $893,396 awarded for that fiscal year; activity UG3 (OTHER_NIH); PI KUO, LAWRENCE C; recipient as written: MEBIAS DISCOVERY, INC., NEW HAVEN, CT. Biased Mu-Opioid Receptor Analgesics source ↗

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