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COMPANY

Bausch + Lomb

HQ: Bridgewater, NJ (US office) source · bausch.com ↗

FDA-cleared device company Clinical Phase 3

Location: Bridgewater, NJ (US office) · source · Oct 12, 2026

Profile checked Oct 10, 2026

Keywords: Myopia Astigmatism Contact Lens Wearer Dry Eye Disease Cataract Dry Eye Refractive Ametropia Presbyopia Contact Lens Wear Ocular Redness Myopic Astigmatism Allergic Conjunctivitis Hyperopia Glaucoma Postoperative Pain Ocular Pain Posterior Capsule Opacification Seasonal Allergic Conjunctivitis Hyperopia and Myopia Primary Open Angle Glaucoma Ocular Hypertension Miebo TENEO 317 Model 2 excimer laser NOV03 All participants received Biotrue ONEday lenses with and without an alternate packaging solution (EPG03) BL1107 enVista MX60E monofocal IOL MX60E TENEO 317 Model 2 (1.28 US) Excimer Laser BL1332

225Trials (company is sponsor)

Timeline

  1. Trial start Phase 2: BL1107 Response and Intensity Guided Dosing for Hyperemia Resolution Trial source ↗
  2. Trial start Phase 1: A Study of BL1332 on Capsaicin-Induced Ocular Pain in Healthy Trial Participants source ↗
  3. Trial start —: Revive Toric RWE Study source ↗
  4. Trial start Phase 2: A Study to Evaluate the Use of Topical Ocular BL1332 for the Management of Postoperative Ocular Pain Following Photorefractive Keratectomy source ↗
  5. Trial start Not phased (device or behavioral study): A Study to Investigate the Safety and Effectiveness of the Technolas® TENEO 317 Model 2 Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Myopia or Myopic Astigmatism source ↗
  6. Trial start Phase 3: A Study to Assess the Long-Term Safety of Lifitegrast/Perfluorohexyloctane Fixed-Dose Combination in Subjects With Dry Eye Disease source ↗
  7. Trial start Not phased (device or behavioral study): Effectiveness and Safety of the TENEO 317 Model 2 Excimer Laser to Treat Myopia With or Without Astigmatism by Transepithelial Photorefractive Keratectomy source ↗
  8. Trial start 2: Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension source ↗
  9. Trial start Phase 2: A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye Disease source ↗
  10. Trial start Phase 1: A Study to Assess Safety, Tolerability, and Pharmacokinetics of Ascending Concentrations of Topical Ocular BL1332 in Healthy Volunteers source ↗
  11. Trial start Phase 4: A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens Wear source ↗
  12. Trial start Not phased (device or behavioral study): Evaluation of a New Laser Refractive Vision Correction Using the TENEO™ 317 Model 2 source ↗
  13. Trial start Phase 3: A Study Comparing the Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution 0.025% With Sodium Hyaluronate Relative to Lumify in Adult Subjects With Ocular Redness source ↗
  14. Trial start Not phased (device or behavioral study): A Post-Market Clinical Follow-Up on Safety and Performance of the Ophthalmic Viscoelastic Devices Eyefill SC and Eyefill MB source ↗
  15. Trial start Not phased (device or behavioral study): A Study to Evaluate Real World Outcomes of the enVista® Aspire (EA) and Aspire Toric (ETA) Intraocular Lens in Subjects Undergoing Cataract Extraction source ↗
  16. Trial start Not phased (device or behavioral study): Clinical Evaluation of the Performance of the enVista® Aspire™ (EA) Lens source ↗
  17. Trial start Not phased (device or behavioral study): Study to Evaluate the Safety and Effectiveness of the enVista® Beyond (EY) EDF Intraocular Lens in Subjects Undergoing Cataract Extraction source ↗
  18. Trial start Phase 4: A Study to Evaluate Corneal Endothelial Cell Density (ECD) in Subjects With Dry Eye Disease (DED) Administering Miebo® (Perfluorohexyloctane Ophthalmic Solution) for 12 Months. source ↗
  19. Trial start —: A Study to Evaluate the enVista® Aspire (EA) Intraocular Lens in Subjects Undergoing Cataract Extraction source ↗
  20. Trial start Phase 4: A Study to Evaluate the Effect of Miebo™ on Preoperative Biometry/Keratometry and Postoperative Refractive Accuracy source ↗
  21. Trial start Not phased (device or behavioral study): A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in Children source ↗
  22. Trial start Phase 4: A Study to Evaluate Early Treatment Outcomes With Miebo™ in Subjects With Dry Eye Disease source ↗
  23. Trial start Not phased (device or behavioral study): 1-Week Dispensing Evaluation of REVIVE™ Toric Soft Contact Lenses source ↗
  24. Trial start —: IC-8 Apthera IOL New Enrollment Post Approval Study source ↗
  25. Trial start Not phased (device or behavioral study): Kalifilcon A Toric Compared to Commercially Available Lenses source ↗

Showing 25 of 50 dated events.

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) Showing 50 of 225

RecordTitlePhaseStatusStartPrimary completion
NCT05264623Safety and Effectiveness of the TENEO 317 Model 2 (1.28 US) Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Hyperopia With or Without AstigmatismNot phased (device or behavioral study)CompletedNov 15, 2022Aug 24, 2026 (actual)
NCT053200421-Week Dispensing Evaluation of Kalifilcon A Toric Contact Lenses Compared to Ultra for AstigmatismNot phased (device or behavioral study)CompletedFeb 14, 2022May 10, 2022 (actual)
NCT07717918A Study of BL1332 on Capsaicin-Induced Ocular Pain in Healthy Trial ParticipantsPhase 1CompletedJul 6, 2026Aug 5, 2026 (actual)
NCT05129488Biotrue ONEday Contact Lenses With EPG03 Packaging Solution Compared to Biotrue ONEday Contact LensesNot phased (device or behavioral study)CompletedSep 15, 2021Sep 20, 2021 (actual)
NCT060537361-Week Dispensing Evaluation of REVIVE™ Toric Soft Contact LensesNot phased (device or behavioral study)CompletedOct 4, 2023Dec 15, 2023 (actual)
NCT07778888BL1107 Response and Intensity Guided Dosing for Hyperemia Resolution TrialPhase 2Not yet recruiting2026-102027-02 (estimated)
NCT053259311-Week Dispensing Evaluation of Kalifilcon A Daily Disposable Multifocal Compared to Ultra for PresbyopiaNot phased (device or behavioral study)CompletedFeb 25, 2022Mar 28, 2022 (actual)
NCT04840563Surface Refractive Index Shift of Kalifilcon A Compared With Dailies Total1 and Precision1 LensesNot phased (device or behavioral study)CompletedApr 7, 2021Apr 15, 2021 (actual)
NCT07168902Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension2CompletedOct 24, 2025May 18, 2026 (actual)
NCT07128628A Study Evaluating the Safety and Efficacy of a Fixed-Dose Combination for Dry Eye DiseasePhase 2CompletedOct 24, 2025May 28, 2026 (actual)
NCT06333015Study to Evaluate the Safety and Effectiveness of the enVista® Beyond (EY) EDF Intraocular Lens in Subjects Undergoing Cataract ExtractionNot phased (device or behavioral study)CompletedAug 7, 2024Jun 11, 2026 (actual)
NCT06346340A Study to Evaluate the Effect of Miebo™ on Preoperative Biometry/Keratometry and Postoperative Refractive AccuracyPhase 4CompletedApr 30, 2024Feb 24, 2025 (actual)
NCT06594185A Study to Evaluate Real World Outcomes of the enVista® Aspire (EA) and Aspire Toric (ETA) Intraocular Lens in Subjects Undergoing Cataract ExtractionNot phased (device or behavioral study)CompletedAug 29, 2024May 21, 2025 (actual)
NCT06803654A Study Comparing the Efficacy and Safety of Brimonidine Tartrate Ophthalmic Solution 0.025% With Sodium Hyaluronate Relative to Lumify in Adult Subjects With Ocular RednessPhase 3CompletedMay 22, 2025Jun 29, 2025 (actual)
NCT06479148Clinical Evaluation of the Performance of the enVista® Aspire™ (EA) LensNot phased (device or behavioral study)TerminatedAug 15, 2024Dec 12, 2024 (actual)
NCT06767917A Post-Market Clinical Follow-Up on Safety and Performance of the Ophthalmic Viscoelastic Devices Eyefill SC and Eyefill MBNot phased (device or behavioral study)CompletedNov 26, 2024Mar 25, 2026 (actual)
NCT07412496A Study to Evaluate the Use of Topical Ocular BL1332 for the Management of Postoperative Ocular Pain Following Photorefractive KeratectomyPhase 2Not yet recruiting2026-042027-02 (estimated)
NCT07377474A Study to Investigate the Safety and Effectiveness of the Technolas® TENEO 317 Model 2 Excimer Laser for Laser In Situ Keratomileusis (LASIK) Surgery to Treat Myopia or Myopic AstigmatismNot phased (device or behavioral study)Not yet recruiting2026-042027-09 (estimated)
NCT06978244A Study to Assess Safety, Tolerability, and Pharmacokinetics of Ascending Concentrations of Topical Ocular BL1332 in Healthy VolunteersPhase 1Active, not recruitingJul 29, 20252026-11 (estimated)
NCT06060041IC-8 Apthera IOL New Enrollment Post Approval StudyNot listedRecruitingSep 8, 2023Sep 30, 2027 (estimated)
NCT07054606A Study to Evaluate Concomitant Perfluorohexyloctane Use With Contact Lens WearPhase 4CompletedJul 2, 2025Nov 3, 2025 (actual)
NCT07111013A Study to Assess the Long-Term Safety of Lifitegrast/Perfluorohexyloctane Fixed-Dose Combination in Subjects With Dry Eye DiseasePhase 3Withdrawn2025-122027-04 (estimated)
NCT06785194Revive Toric RWE StudyNot listedNot yet recruiting2026-052026-07 (estimated)
NCT06309953A Study to Evaluate Early Treatment Outcomes With Miebo™ in Subjects With Dry Eye DiseasePhase 4CompletedFeb 28, 2024Jun 17, 2024 (actual)
NCT05984290Study of Safety and Effectiveness of the Boston Orthokeratology Shaping Lens in the Arise Orthokeratology LensNot phased (device or behavioral study)CompletedJul 11, 2023Jun 27, 2024 (actual)
NCT051269532-Hour Dispensing Evaluation of Samfilcon A Lenses With EPG01 Packaging Solution Compared to Commercially Available B+L Ultra LensesNot phased (device or behavioral study)CompletedSep 21, 2021Sep 23, 2021 (actual)
NCT05815758Evaluation of the Safety and Pharmacokinetics of Brimonidine Tartrate 0.025%/Ketotifen Fumarate 0.035% Combination Ophthalmic SolutionPhase 3CompletedApr 20, 2023Sep 18, 2023 (actual)
NCT05129124Insertion Clinical Study to Evaluate the Orientation Characteristics of Multiple Kalifilcon A Daily Disposable Toric LD213001 Contact LensesNot phased (device or behavioral study)CompletedNov 30, 2021Jan 13, 2022 (actual)
NCT05723770Effects of NOV03 on the Tear FilmPhase 4CompletedAug 14, 2023Dec 23, 2023 (actual)
NCT06069609Orientation Characteristics of Daily Disposable Toric Contact LensesNot phased (device or behavioral study)CompletedAug 11, 2023Aug 15, 2023 (actual)
NCT05591755Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination in Adults With Seasonal Allergic ConjunctivitisPhase 3CompletedNov 18, 2022Aug 9, 2023 (actual)
NCT05129072Insertion Clinical Study to Evaluate the Aberration Characteristics of Kalifilcon A Toric LensesNot phased (device or behavioral study)CompletedAug 25, 2021Sep 24, 2021 (actual)
NCT06997003Evaluation of a New Laser Refractive Vision Correction Using the TENEO™ 317 Model 2Not phased (device or behavioral study)RecruitingJun 16, 20252026-09 (estimated)
NCT06618547Effectiveness and Safety of the TENEO 317 Model 2 Excimer Laser to Treat Myopia With or Without Astigmatism by Transepithelial Photorefractive KeratectomyNot phased (device or behavioral study)Not yet recruiting2025-112026-11 (estimated)
NCT06305663A Study to Evaluate the Safety and Efficacy of the Bausch + Lomb Myopia Control Lens for the Correction of Myopic Ametropia and Slowing the Progression of Myopia in ChildrenNot phased (device or behavioral study)RecruitingMar 29, 2024Jan 31, 2027 (estimated)
NCT05565937A Study to Evaluate the Safety and Effectiveness of a Contact Lens Cleaning and Disinfecting SolutionNot phased (device or behavioral study)CompletedApr 12, 2023Feb 28, 2024 (actual)
NCT06333028A Study to Evaluate the enVista® Aspire (EA) Intraocular Lens in Subjects Undergoing Cataract ExtractionNot listedCompletedMay 30, 2024Mar 13, 2025 (actual)
NCT04149899Safety and IOP-Lowering Effects of WB007Phase 1/Phase 2CompletedNov 14, 2019Jan 31, 2021 (actual)
NCT05579730Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination for the Treatment of Allergic ConjunctivitisPhase 3CompletedOct 12, 2022Jul 22, 2023 (actual)
NCT03603600Evaluate the Safety and Effectiveness of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular LensNot phased (device or behavioral study)CompletedMay 31, 2018May 4, 2023 (actual)
NCT06565650A Study to Evaluate Corneal Endothelial Cell Density (ECD) in Subjects With Dry Eye Disease (DED) Administering Miebo® (Perfluorohexyloctane Ophthalmic Solution) for 12 Months.Phase 4Active, not recruitingJul 31, 20242025-11 (estimated)
NCT06098937Kalifilcon A Toric Compared to Commercially Available LensesNot phased (device or behavioral study)CompletedSep 5, 2023Sep 27, 2023 (actual)
NCT04139798Perfluorohexylcotane (NOV03) for the Treatment of Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (Gobi Study)Phase 3CompletedJul 20, 2020Mar 12, 2021 (actual)
NCT04224155Clinical Study to Evaluate the Safety and Performance of the enVista® One-Piece Hydrophobic Acrylic Trifocal Intraocular Lens in Subjects Undergoing Cataract ExtractionNot phased (device or behavioral study)CompletedMar 10, 2020Jun 14, 2022 (actual)
NCT01650584Evaluation of Ocular Comfort With ISTA Tears vs SystaneNot phased (device or behavioral study)Completed2012-062012-12 (actual)
NCT05360784"Efficacy and Safety of Brimonidine Tartrate Preservative-Free Formulation in Adults With Ocular Redness"Phase 3CompletedMay 13, 2022Nov 23, 2022 (actual)
NCT04567329Effect of NOV03 on Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (Mojave Study)Phase 3CompletedNov 18, 2020Aug 30, 2021 (actual)
NCT04175340A Safety and Effectiveness Study of a New Preservative Free Rewetting DropNot phased (device or behavioral study)CompletedNov 7, 2019Feb 17, 2020 (actual)
NCT04111757A Study With Technolas® TENEO 317 Model 2 Excimer Laser to Treat Participants With Myopia or Myopic AstigmatismNot phased (device or behavioral study)CompletedJul 25, 2019Aug 6, 2021 (actual)
NCT04192630A Study of B + L Ophthalmic Viscosurgical Device (OVD) CVisc50Not phased (device or behavioral study)CompletedNov 26, 2019Jan 31, 2022 (actual)
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