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COMPANY

Halia Therapeutics

HQ: Lehi, UT source · haliatx.com ↗ · Mountain

Clinical Phase 2

Location: Lehi, UT · source · Oct 14, 2026

Profile checked Oct 10, 2026

Keywords: Myelodysplastic Syndromes Anemia Myelodysplastic Syndrome Anemia in Myelodysplastic Syndromes Alzheimers Disease Type 2 Diabetes Mellitus Obesity HT-6184 HT-4253 Ofirnoflast

7Trials (company is sponsor)

Funding and NIH signals

Job counts as of Oct 18, 2026. All funding and NIH signals

Timeline

  1. Trial start Phase 2: A Study to Evaluate Ofirnoflast in Adults With Very Low- to Intermediate-risk Myelodysplastic Syndromes Requiring Red Blood Cell Transfusions source ↗
  2. Trial start Phase 2: Study to Evaluate the Effect of HT-4253 for the Prevention of Alzheimer's Disease in APOE4 Carriers source ↗
  3. Trial start Phase 2: A Ph2 Study to Evaluate the Safety, Efficacy and Tolerability of HT-6184 and Semaglutide in Obese Participants With T2DM source ↗
  4. Trial start Phase 1: Study to Evaluate HT-4253 in Healthy Subjects source ↗
  5. Trial start Phase 2: Evaluating Ability of HT-6184 to Reduce Inflammation and Pain After Third Molar Extraction source ↗
  6. Trial start 2: A Phase 2a Study of HT-6184 in Subjects With IPSS-R Very Low, Low or Intermediate Risk MDS and Anemia source ↗
  7. Trial start Phase 1: Study to Evaluate HT-6184 in Healthy Subjects source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Clinical trials (lead sponsor) 7

RecordTitlePhaseStatusStartPrimary completion
NCT07738510A Study to Evaluate Ofirnoflast in Adults With Very Low- to Intermediate-risk Myelodysplastic Syndromes Requiring Red Blood Cell TransfusionsPhase 2Not yet recruiting2026-112028-10 (estimated)
NCT07052006A Phase 2a Study of HT-6184 in Subjects With IPSS-R Very Low, Low or Intermediate Risk MDS and Anemia2Active, not recruitingDec 9, 2023Jan 8, 2026 (actual)
NCT07399171Study to Evaluate the Effect of HT-4253 for the Prevention of Alzheimer's Disease in APOE4 CarriersPhase 2RecruitingMay 12, 20262028-02 (estimated)
NCT07172867A Ph2 Study to Evaluate the Safety, Efficacy and Tolerability of HT-6184 and Semaglutide in Obese Participants With T2DMPhase 2WithdrawnJan 6, 2026Jan 23, 2026 (actual)
NCT06537817Study to Evaluate HT-4253 in Healthy SubjectsPhase 1CompletedSep 17, 2024May 12, 2025 (actual)
NCT06241742Evaluating Ability of HT-6184 to Reduce Inflammation and Pain After Third Molar ExtractionPhase 2CompletedFeb 12, 2024Apr 30, 2024 (actual)
NCT05447546Study to Evaluate HT-6184 in Healthy SubjectsPhase 1CompletedJun 15, 2022Jul 20, 2023 (actual)
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