COMPANY
Scholar Rock, Inc.
FDA-approved therapeutic company Clinical Phase 3
Hiring
| Title | Location (from posting) | Employer posted | First seen |
|---|---|---|---|
| Senior Director, Patient Advocacy & Communications Lead, EMEA | Zug | Oct 20, 2026 | Oct 21, 2026 |
| Director, External & CMC Quality Assurance | Cambridge, MA | Oct 8, 2026 | Oct 11, 2026 |
| Director, International Indirect Tax | Dublin | Oct 8, 2026 | Oct 11, 2026 |
| Director, Domestic Tax | Cambridge, MA | Oct 8, 2026 | Oct 11, 2026 |
| Senior Manager/Associate Director, Accounting EMEA | Dublin | Oct 7, 2026 | Oct 11, 2026 |
Trial and FDA signals
- New trial + clinical hiring Started a Phase 2 trial (NCT07435129, actual start Jul 30, 2026); since then posted 4 clinical-operations roles. ClinicalTrials.gov NCT07435129 (Jul 30, 2026)
Evidence (1 event)
- Jul 30, 2026 · ClinicalTrials.gov NCT07435129
leadSponsor.name='Scholar Rock, Inc.'; phases=['PHASE2']; overallStatus=RECRUITING; startDateStruct={date:2026-07-30,type:ACTUAL}; studyFirstPostDate=2026-02-27; briefTitle='Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD'
- Jul 30, 2026 · ClinicalTrials.gov NCT07435129
- Drug approval + hiring FDA novel approval for ISEMBYLD (BLA 761463, Sep 11, 2026); since then posted 3 manufacturing/quality or commercial roles. FDA BLA 761463 (Sep 11, 2026)
Evidence (1 event)
- Sep 11, 2026 · FDA BLA 761463
openFDA drugsfda: application_number=BLA761463; sponsor_name='SCHOLAR ROCK INC'; submission_type=ORIG; submission_number=1; submission_status=AP; submission_status_date=20260911; submission_class_code=TYPE 1; brand_name=['ISEMBYLD']
- Sep 11, 2026 · FDA BLA 761463
Timeline
- FDA FDA New drug/biologic (novel): ISEMBYLD (apitegromab-mstn) — BLA761463, Sep 11, 2026. Applicant at approval: Scholar Rock, Inc. source ↗
- Trial start 2: Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD source ↗
- Trial start Phase 1: A Single- and Multiple-Ascending Dose Study of SRK-439 in Healthy Adults source ↗
- Trial start Phase 2: A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy source ↗
- Trial start Phase 2: Efficacy and Safety of Apitegromab for the Treatment of Adults Who Are Overweight or Obese source ↗
- Trial start Phase 3: Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab source ↗
- Trial start Phase 3: Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam source ↗
- Trial start Phase 1: SRK-181 Alone or in Combination With Anti-PD-(L)1 Antibody Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (DRAGON) source ↗
- Trial start Phase 2: An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy source ↗
Upcoming milestones
- Nov 1, 2026 (ESTIMATED) · Phase 3 · Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab · NCT05626855
- Dec 17, 2026 (ESTIMATED) · Phase 1 · A Single- and Multiple-Ascending Dose Study of SRK-439 in Healthy Adults · NCT07444294
- 2028-06 (ESTIMATED) · 2 · Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD · NCT07435129
- 2028-11 (ESTIMATED) · Phase 2 · A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy · NCT07047144
Clinical trials (lead sponsor) 9
| Record | Title | Phase | Status | Start | Primary completion |
|---|---|---|---|---|---|
| NCT07047144 | A Study to Evaluate How Apitegromab Works in Subjects Who Are Less Than 2 Years Old and Have Spinal Muscular Atrophy | Phase 2 | Recruiting | Sep 15, 2025 | 2028-11 (estimated) |
| NCT07435129 | Phase 2 Study Evaluating Apitegromab for the Treatment of FSHD | 2 | Recruiting | Jul 30, 2026 | 2028-06 (estimated) |
| NCT05626855 | Long-Term Safety & Efficacy of Apitegromab in Patients With SMA Who Completed Previous Trials of Apitegromab | Phase 3 | Active, not recruiting | Apr 17, 2023 | Nov 1, 2026 (estimated) |
| NCT06877689 | EAP of Apitegromab for Patients With Spinal Muscular Atrophy | Not listed | No longer available | Not listed | Not listed |
| NCT07444294 | A Single- and Multiple-Ascending Dose Study of SRK-439 in Healthy Adults | Phase 1 | Recruiting | Nov 21, 2025 | Dec 17, 2026 (estimated) |
| NCT06445075 | Efficacy and Safety of Apitegromab for the Treatment of Adults Who Are Overweight or Obese | Phase 2 | Completed | May 21, 2024 | Mar 4, 2025 (actual) |
| NCT05156320 | Efficacy and Safety of Apitegromab in Patients With Later-Onset Spinal Muscular Atrophy Treated With Nusinersen or Risdiplam | Phase 3 | Completed | Apr 14, 2022 | Dec 18, 2024 (actual) |
| NCT04291079 | SRK-181 Alone or in Combination With Anti-PD-(L)1 Antibody Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (DRAGON) | Phase 1 | Completed | Apr 23, 2020 | Apr 14, 2025 (actual) |
| NCT03921528 | An Active Treatment Study of SRK-015 in Patients With Type 2 or Type 3 Spinal Muscular Atrophy | Phase 2 | Completed | Apr 22, 2019 | Jan 19, 2021 (actual) |
FDA records (last 2 years)
- FDA New drug/biologic (novel): ISEMBYLD (apitegromab-mstn) — BLA761463, Sep 11, 2026. Applicant at approval: Scholar Rock, Inc. source ↗
Raises and investors new
- InvestorListed in the portfolio of ARCH Venture Partners (captured Oct 12, 2026). portfolio page ↗
Open jobs 35
| Title | Location (from posting, not HQ) | Employer posted | First seen | Level |
|---|---|---|---|---|
| Senior Director, Patient Advocacy & Communications Lead, EMEA | Zug | Oct 20, 2026 | Oct 21, 2026 | Not stated |
| Director, External & CMC Quality Assurance | Cambridge, MA | Oct 8, 2026 | Oct 11, 2026 | Senior |
| Director, International Indirect Tax | Dublin | Oct 8, 2026 | Oct 11, 2026 | Senior |
| Director, Domestic Tax | Cambridge, MA | Oct 8, 2026 | Oct 11, 2026 | Senior |
| Senior Manager/Associate Director, Accounting EMEA | Dublin | Oct 7, 2026 | Oct 11, 2026 | Senior |
| Associate Director/ Director FP&A EMEA | Zug | Oct 7, 2026 | Oct 11, 2026 | Senior |
| Office Manager and Executive Administrative Coordinator | Miami, FL | Oct 5, 2026 | Oct 11, 2026 | Mid |
| Sr. Scientist, Antibody Engineering | Cambridge, MA | Oct 5, 2026 | Oct 11, 2026 | Senior |
| Associate Director, IT Service Delivery & Support | Cambridge, MA | Oct 5, 2026 | Oct 11, 2026 | Senior |
| Sr. Director, Infrastructure & Operations | Cambridge, MA | Oct 5, 2026 | Oct 11, 2026 | Senior |
| Sr. Director, Enterprise Business Applications | Cambridge, MA | Oct 5, 2026 | Oct 11, 2026 | Senior |
| Workplace Services Senior Manager | Cambridge, MA | Sep 30, 2026 | Oct 11, 2026 | Senior |
| Senior Manager, Lab Operations | Cambridge, MA | Sep 30, 2026 | Oct 11, 2026 | Senior |
| Director, Market Insights | Cambridge, MA | Sep 29, 2026 | Oct 11, 2026 | Senior |
| Payroll Manager | Cambridge, MA | Sep 28, 2026 | Oct 11, 2026 | Mid |
| Principal Scientist, Bioanalytical Specialist | Cambridge, MA | Sep 28, 2026 | Oct 11, 2026 | Senior |
| Principal Scientist, Biomarker Development | Cambridge, MA | Sep 25, 2026 | Oct 11, 2026 | Senior |
| Associate Director/Senior Clinical Trial Manager | Cambridge, MA | Sep 23, 2026 | Oct 11, 2026 | Senior |
| Medical Director/Sr Director, Clinical Research | Cambridge, MA | Sep 22, 2026 | Oct 11, 2026 | Senior |
| Senior Manager /Associate Director, Biostatistics | Cambridge, MA | Sep 22, 2026 | Oct 11, 2026 | Senior |
| Senior Director, Device Engineering | Cambridge, MA | Sep 18, 2026 | Oct 11, 2026 | Senior |
| Director, Pricing & Contracting Operations | Cambridge, MA | Sep 17, 2026 | Oct 11, 2026 | Senior |
| Associate Director, Regulatory Strategy | Cambridge, MA | Sep 10, 2026 | Oct 11, 2026 | Senior |
| Associate Director/Director, Medical Operations | Cambridge, MA | Sep 2, 2026 | Oct 11, 2026 | Senior |
| Director, Global Quality Control | Cambridge, MA | Sep 1, 2026 | Oct 11, 2026 | Senior |
| Senior Engineer, Downstream Manufacturing Science & Technology (MSAT) | Cambridge, MA | Aug 31, 2026 | Oct 11, 2026 | Senior |
| Senior Manager, Contracts | Cambridge, MA | Aug 25, 2026 | Oct 11, 2026 | Senior |
| Senior Accountant | Cambridge, MA | Aug 18, 2026 | Oct 11, 2026 | Senior |
| Senior Manager / Associate Director, HCP Marketing (US) | Cambridge, MA | Aug 10, 2026 | Oct 11, 2026 | Senior |
| Director/Sr. Director, Clinical Pharmacology | Cambridge, MA | Aug 4, 2026 | Oct 11, 2026 | Senior |
| Associate Director/Director, Patient Marketing (US) | Cambridge, MA | Jul 28, 2026 | Oct 11, 2026 | Senior |
| Associate Director/Director, Clinical Operations Compliance | Cambridge, MA | Jul 7, 2026 | Oct 11, 2026 | Senior |
| Sr. Director, HR Business Partner (R & D and Tech Ops & Quality) | Cambridge, MA | Jun 8, 2026 | Oct 11, 2026 | Senior |
| Vice President, Head of Regulatory Strategy | Cambridge, MA | Mar 16, 2026 | Oct 11, 2026 | Executive |
| Sr. Medical Director, Drug Safety & Pharmacovigilance | Cambridge, MA | Jul 16, 2025 | Oct 11, 2026 | Senior |
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