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COMPANY

Locus Biosciences

HQ: Morrisville, NC source · locus-bio.com ↗ · Southeast

Clinical Phase 2

Location: Morrisville, NC · source · Oct 14, 2026

Profile checked Oct 10, 2026

Keywords: Urinary Tract Infections LBP-EC01

2Trials (company is sponsor)2NIH grants

Timeline

  1. Grant Government grant: $3.3M (total, as published), announced Jan 7, 2026. Source: company's own press page. source ↗
  2. Partnership Partnership / licensing announced Oct 28, 2025. Source: company's own press page. source ↗
  3. Trial start Phase 2: A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial) source ↗
  4. Trial start Phase 1: Safety, Tolerability, and PK of LBP-EC01 in Patients With Lower Urinary Tract Colonization Caused by E. Coli source ↗

Upcoming milestones

Estimated primary completion per ClinicalTrials.gov. Dates move.

Funding

Last 2 years.

Clinical trials (lead sponsor) 2

RecordTitlePhaseStatusStartPrimary completion
NCT05488340A Study of LBP-EC01 in the Treatment of Acute Uncomplicated UTI Caused by Drug Resistant E. Coli (ELIMINATE Trial)Phase 2RecruitingJul 13, 20222027-06 (estimated)
NCT04191148Safety, Tolerability, and PK of LBP-EC01 in Patients With Lower Urinary Tract Colonization Caused by E. ColiPhase 1CompletedDec 30, 2019Nov 19, 2020 (actual)

NIH awards 2

Annual award amounts. Total $7.9M.

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